The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
Identifieur interne : 000126 ( Istex/Curation ); précédent : 000125; suivant : 000127The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
Auteurs : Kishna Kalicharran [Canada] ; Samuel Dales [Canada]Source :
- Trends in Microbiology [ 0966-842X ] ; 1996.
English descriptors
- Teeft :
- Axonal, Bioi, Cell bioi, Disease process, Dissemination, Ecretory pathway, Ependymal cells, Hippocampal, Hippocampal neurons, Inoculation, Intracranial inoculation, Intranasal inoculation, Jhmv, Microtubule, Murine coronavirus, Natl acad, Neuron, Neuronal, Neuronal cells, Neuronal surface, Progeny virions, Same neurons, Scale bars, Secondary antibodies, Sequence identities, Sequence similarities, Trafficking, Viral, Viral components, Virion, Virol, Virology.
Abstract
Abstract: The replication of JHM, a murine coronavirus, provides a useful model of the assembly and dissemination of viral components in neuronal cells. Involvement of microtubules in virus trafficking is an important feature which may explain dissemination of the infection from primary cell targets at olfactory, hippocampal and cerebellar sites within the central nervous system, resulting in severe neuropathies.
Url:
DOI: 10.1016/0966-842X(96)10045-7
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue</title><author><name sortKey="Kalicharran, Kishna" sort="Kalicharran, Kishna" uniqKey="Kalicharran K" first="Kishna" last="Kalicharran">Kishna Kalicharran</name><affiliation wicri:level="1"><mods:affiliation>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario, Canada N6A 5C1</mods:affiliation><country>Canada</country><wicri:regionArea>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Dales, Samuel" sort="Dales, Samuel" uniqKey="Dales S" first="Samuel" last="Dales">Samuel Dales</name><affiliation wicri:level="1"><mods:affiliation>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario, Canada N6A 5C1</mods:affiliation><country>Canada</country><wicri:regionArea>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:0267E6833287FB7BB2F95EE32CB09208996A0885</idno><date when="1996" year="1996">1996</date><idno type="doi">10.1016/0966-842X(96)10045-7</idno><idno type="url">https://api.istex.fr/ark:/67375/6H6-RMT54M6V-W/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000158</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000158</idno><idno type="wicri:Area/Istex/Curation">000126</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue</title><author><name sortKey="Kalicharran, Kishna" sort="Kalicharran, Kishna" uniqKey="Kalicharran K" first="Kishna" last="Kalicharran">Kishna Kalicharran</name><affiliation wicri:level="1"><mods:affiliation>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario, Canada N6A 5C1</mods:affiliation><country>Canada</country><wicri:regionArea>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Dales, Samuel" sort="Dales, Samuel" uniqKey="Dales S" first="Samuel" last="Dales">Samuel Dales</name><affiliation wicri:level="1"><mods:affiliation>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario, Canada N6A 5C1</mods:affiliation><country>Canada</country><wicri:regionArea>Dept of Microbiology and Immunology, Health Sciences Centre, The University of Western Ontario, London, Ontario</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Trends in Microbiology</title><title level="j" type="abbrev">TIMI</title><idno type="ISSN">0966-842X</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1996">1996</date><biblScope unit="volume">4</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="264">264</biblScope><biblScope unit="page" to="269">269</biblScope></imprint><idno type="ISSN">0966-842X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0966-842X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Axonal</term><term>Bioi</term><term>Cell bioi</term><term>Disease process</term><term>Dissemination</term><term>Ecretory pathway</term><term>Ependymal cells</term><term>Hippocampal</term><term>Hippocampal neurons</term><term>Inoculation</term><term>Intracranial inoculation</term><term>Intranasal inoculation</term><term>Jhmv</term><term>Microtubule</term><term>Murine coronavirus</term><term>Natl acad</term><term>Neuron</term><term>Neuronal</term><term>Neuronal cells</term><term>Neuronal surface</term><term>Progeny virions</term><term>Same neurons</term><term>Scale bars</term><term>Secondary antibodies</term><term>Sequence identities</term><term>Sequence similarities</term><term>Trafficking</term><term>Viral</term><term>Viral components</term><term>Virion</term><term>Virol</term><term>Virology</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The replication of JHM, a murine coronavirus, provides a useful model of the assembly and dissemination of viral components in neuronal cells. Involvement of microtubules in virus trafficking is an important feature which may explain dissemination of the infection from primary cell targets at olfactory, hippocampal and cerebellar sites within the central nervous system, resulting in severe neuropathies.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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